Muttaburrasaurus was a large four-legged herbivore that was capable of rearing onto two legs. It was very similar to Iguanodon. Like it, its three middle fingers were joined together into a hoof-like pad, for walking on.

Muttaburrasaurus had very powerful jaws which were equipped with shearing teeth. These were probably an adaptation for eating tough vegetation such as cycads, which were common in this part of Australia at the time. It also had an enlarged hollow upward-bulging muzzle, that might have been used to produce distinctive calls or for display purposes. However, as no fossilised nasal tissue has been found, this remains conjectural.

It is known from one partial skeleton found at Muttaburra, Queensland, Australia.